Defonase 100 ml

Product Name

• Defonase, Syrup, Relieves Cold & Allergy - 100 Ml

Scientific Name

• Loratadine 5 Mg + Pseudoephedrine 60 Mg /5 Ml Syrup

Category Of Defonase Syrup

• Allergy & Cold Drugs

Mechanism Of Action Of Loratadine & Pseudoephedrine

• H1 histamine receptor antagonist; competes for H1-receptor sites in target cells in the respiratory tract, blood vessels, and gastrointestinal tract.
• Loratadine is a non-sedative second generation
• Pseudoephedrine is a sympathomimetic with a mixed mechanism of action, direct and indirect.
• Pseudoephedrine is a decongestant used for reducing nasal congestion caused by allergies or the common cold.
• Pseudoephedrine causes blood vessels in the nasal passages to shrink (vasoconstrictor).
• Vasoconstriction reduces nasal congestion by preventing fluid from draining from blood vessels into nasal passages.

Therapeutic Indications Of Defonase Syrup

• This drug relieves symptoms associated with allergic rhinitis, such as:

1. nasal and sinus congestion
2. sneezing
3. runny nose
4. watery, itchy eyes

Method Of Administration Of Defonase Syrup

• Always take this medicine exactly as your doctor or pharmacist has told you.
• Check with your doctor or pharmacist if you are not sure.
• Shake well before uses
• It does not matter if you take loratadine/pseudoephedrine before or after food.
• The average doses:

1. Adults and Children 6 - 12 years of age (body weight >30 kg): 5ml syrup (one teaspoonful) once a day.
2. Children 6 - 12 years (body weight <30 kg): 2.5ml syrup (half teaspoonful) once a day.
3. Children below 6 years of age: Do not use

• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Defonase Syrup

• Although the following side effects are not common in everyone, some patients may complain from:
• Trouble sleeping

1. Dry mouth
2. Headache
3. Sleepiness
4. Nervousness
5. Dizziness
6. Fatigue

Pregnancy & Breastfeeding Precautions While Taking Defonase Syrup

• If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
• Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding

Non-Pharmacological Treatments & Advice To Reduce Allergy

• Stay hydrated: Drink lots of water to thin mucus.
• Inhale steam: Take a hot shower, or boil water and pour it into a bowl, face the bowl (stay at least 1 foot away), place a towel over the back of your head to form a tent, and inhale.
• Use a humidifier, for example, Vicks Air Humidifier, to loosen mucus
• Avoid inhaled irritants such as dust, perfumes, or pollutants. Wear face mask to reduce the exposure to the allergen
• Sometimes smoke irritates your airways and causes inflammation that turns into bronchitis. Stopping smoking will help you to get rid of your cough.
• Lozenges like Strepsils soothes an irritated throat

Warnings & Special Precautions while Taking Defonase Syrup

• Before you use this medicine talk to your doctor or pharmacist:

1. If you suffer from bronchial asthma
2. If you have or have had a peptic ulcer
3. If you suffer from Hepatic disease
4. If you suffer from Hepatic disease
5. If you suffer from Renal impairment
6. If you are allergic to any of the ingredients of this medicine.

• Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medications including over-the-counter non-prescription medicines, prescription medicines, herbal supplements, vitamins, and supplements.

Storage Conditions Of Defonase Syrup

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

For More Information About Loratadine

• Ask your physician or pharmacist
• Visit SFDA website
• Visit Medscape at Information About Loratadine
• Visit Drugbank at Information About Loratadine
• Visit drugs.com at Information About Loratadine